The matRad software tutorial for radiotherapy planning

Authors

DOI:

https://doi.org/10.21167/cqdv25e25002

Keywords:

Mathematics Applied to Physics, Radiation Therapy, Operational Research, Optimization

Abstract

The matRad is an effective software for learning and developing advanced techniques in radiotherapy planning. It was developed by the German Cancer Research Center DKFZ to plan treatments that utilize photons, protons, and carbon ions, and it stands out for calculating dose with inverse planning and presenting treatment plans. The use of this program contributes to the enhancement of clinical outcomes by delivering a more conformal dose to the tumor and reducing side effects. This article describes the steps for obtaining, installing, and using the matRad software. An application in liver cancer treatment is presented to develop a radiotherapy plan, investigating the entire graphical interface.

Author Biographies

Daniela Renata Cantane, São Paulo State University (Unesp), Institute of Biosciences, Botucatu

Daniela has Graduation at Bacharelado em Matemática São José do Rio Preto from Universidade Estadual Paulista Júlio de Mesquita Filho (2001), master's at Computer Science from Universidade de São Paulo (2004) and doctorate at Electric Engineering from Universidade Estadual de Campinas (2009). Has experience in Production Engineering, focusing on Linear, Nonlinear, Mixing and Dynamic Programming, acting on the following subjects: linear optimization, factorization update, simplex, sparse matrix and heuristics.

Richard Castro Junior, São Paulo State University (Unesp), Institute of Biosciences, Botucatu

Graduated in Physics of Materials from São Paulo State University "Júlio de Mesquita Filho" UNESP (2021). Research project: Modeling and Molecular Simulations Group, Bauru - SP; title: Functionalization of TiO2-anatase nanotubes with silver atoms - scholarship from the National Council for Scientific and Technological Development, CNPq (2018-2019). Specialized in Diagnostic and Therapeutic Innovations at Medical School (FMB) of São Paulo State University (Unesp) - scholarship from the State Department of Health, SES - SP (2021-2022). Currently, Master's student in Biometrics Postgraduate Program at Institute of Biosciences, UNESP Botucatu - scholarship from the Coordination of Improvement of Higher Education Personnel (CAPES).Bachelor's degree in Materials Physics from São Paulo State University "Júlio de Mesquita Filho" UNESP (2021), with a focus on research in the Molecular Modeling and Simulation Group in Bauru-SP. During undergraduate studies, participated in the research project "Functionalization of TiO2-anatase nanotubes with silver atoms," funded by the National Council for Scientific and Technological Development, CNPq (2018-2019). Holds a specialization in Diagnostic and Therapeutic Innovations from the Hospital das Clinicas of the Botucatu Medical School, HCFMB, with a scholarship from the São Paulo State Department of Health, SES-SP (2022). Currently, holds a Master's degree in Biometry (2024) from the Institute of Biosciences, UNESP Botucatu, with a scholarship from the Coordination of Improvement of Higher Education Personnel, CAPES, and is a Ph.D. student in the Biometry Graduate Program at the same institute and has a CAPES scholarship.

Diogo José Sousa Leão, São Paulo State University (Unesp), Institute of Biosciences, Botucatu

Undergraduate student of the Bachelor's Degree in Medical Physics, Class XIX, São Paulo State University Júlio de Mesquita Filho, Institute of Biosciences of Botucatu. Currently a IC scholarship holder at VUNESP, through the Inclusion of Public School Students in the University program, with a study project on radiotherapy planning using software.              

Felipe Melo Silva, São Paulo State University (Unesp), Institute of Biosciences, Botucatu

Studying Medical Physics at the São Paulo State University Júlio de Mesquita Filho (Unesp) at the Institute of Biosciences, Botucatu Campus. Student with a PIBIC scientific initiation scholarship, working in the Department of Biodiversity and Biostatistics, with the project: Planning Cancer Treatment by Proton Beam Radiation with MatRad Software.

Published

2025-07-07

How to Cite

CANTANE, D. R.; CASTRO JUNIOR, R.; LEÃO, D. J. S.; SILVA, F. M. The matRad software tutorial for radiotherapy planning. C.Q.D. - Revista Eletrônica Paulista de Matemática, Bauru, v. 25, p. e25002, 2025. DOI: 10.21167/cqdv25e25002. Disponível em: https://sistemas.fc.unesp.br/ojs/index.php/revistacqd/article/view/463. Acesso em: 11 jul. 2025.

Issue

Section

Edição Especial ERMAC 2024